发明公开
- 专利标题： Neukinase, a downstream protein of neuregulin
- 专利标题（中）： Neuregulin是神经调节蛋白的下游蛋白
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申请号： EP13184566.1申请日： 2007-08-21
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公开(公告)号： EP2730654A2公开(公告)日： 2014-05-14
- 发明人: Zhou, Mingdong
- 申请人： Zensun (Shanghai) Science and Technology Limited
- 申请人地址： No.68 Ju Li Road Zhangjiang Hi-Tech Park Shanghai 201203 CN
- 专利权人： Zensun (Shanghai) Science and Technology Limited
- 当前专利权人： Zensun (Shanghai) Science and Technology Limited
- 当前专利权人地址： No.68 Ju Li Road Zhangjiang Hi-Tech Park Shanghai 201203 CN
- 代理机构： Bezzubova, Olga
- 优先权： US839388P 20060821; US921655P 20070402
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C12N15/12 ; C12N15/52 ; C12N15/63 ; C12N15/85 ; C12N15/86 ; C12N9/48 ; C12N5/16 ; C12N5/22 ; C07H21/00 ; C07K16/16 ; A61K38/45 ; C07K16/40 ; C12Q1/48 ; G01N33/68 ; C12N9/12
摘要：
The present invention relates to an isolated polypeptide comprising an amino acid sequence having at least 70% identity to the amino acid sequence of SEQ ID NO:2 or to the amino acid sequence of SEQ ID NO:25; or encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 2 or the amino acid sequence of SEQ ID NO: 25, wherein the polypeptide is capable of phosphorylating myosin light chain. The present invention also relates to an isolated nucleic acid encoding said polypeptide; a composition and a kit comprising the polypeptide or the nucleic acid; a vector comprising the isolated nucleic acid; an isolated host cell comprising the nucleic acid or the vector; an antibody that specifically binds to the polypeptide of the present invention; and a transgenic non-human animal which expresses the nucleic acid of the present invention. The invention further relates to a method of detecting the presence of a nucleic acid of the present invention; and a method of producing a neukinase polypeptide of the present invention.
公开/授权文献
- EP2730654B1 Neukinase, a downstream protein of neuregulin 公开/授权日：2017-03-01
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