发明公开
- 专利标题： SUBSTITUTED BENZOFURAN COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
- 专利标题（中）： 取代使用苯并呋喃和方法病毒病的治疗
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申请号： EP12829739申请日： 2012-08-16
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公开(公告)号： EP2753611A4公开(公告)日： 2015-03-11
- 发明人: MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , HABERMANN JOERG , KOCH UWE , NARJES FRANK , LI PENG , PENG XUANJIA , SOLL RICHARD , WU HAO , PALANI ANANDAN , DAI XING , LIU HONG , HE SHUWEN , DANG QUNG
- 申请人： MERCK SHARP & DOHME , MSD ITALIA SRL
- 专利权人： MERCK SHARP & DOHME,MSD ITALIA SRL
- 当前专利权人： MERCK SHARP & DOHME,MSD ITALIA SRL
- 优先权： CN2011079463 2011-09-08
- 主分类号： C07D405/04
- IPC分类号： C07D405/04 ; A61K31/343 ; A61K31/4045 ; A61K31/416 ; A61K31/4184 ; A61K31/4375 ; A61K31/4439 ; A61K31/52 ; A61K45/06 ; A61P31/12 ; A61P31/14 ; C07D405/14 ; C07D471/04 ; C07D473/00 ; C07D498/04
摘要：
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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