发明公开
- 专利标题： METHODS AND COMPOSITIONS FOR MODIFICATION OF THE HPRT LOCUS
- 专利标题（中）： 方法和组合物在HPRT座位变化
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申请号： EP12844270申请日： 2012-10-25
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公开(公告)号： EP2771457A4公开(公告)日： 2015-04-08
- 发明人: COST GREGORY J , HOLMES MICHAEL C , KASAHARA NORIYUKI , LAGANIERE JOSEE , MILLER JEFFREY C , PASCHON DAVID , REBAR EDWARD J , URNOV FYODOR , ZHANG LEI
- 申请人： SANGAMO BIOSCIENCES INC , UNIV CALIFORNIA
- 专利权人： SANGAMO BIOSCIENCES INC,UNIV CALIFORNIA
- 当前专利权人： SANGAMO BIOSCIENCES INC,UNIV CALIFORNIA
- 优先权： US201161552309 2011-10-27; US201161556691 2011-11-07
- 主分类号： C12N9/10
- IPC分类号： C12N9/10 ; C12N9/22 ; C12N15/90
摘要：
Nucleases and methods of using these nucleases for modification of an HPRT locus and for increasing the frequency of gene modification at a targeted locus and clones and for generating animals.
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