发明公开
- 专利标题： FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
- 专利标题（中）： 因子VIII组合物和方法进行生产及其用途
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申请号： EP12868427.1申请日： 2012-07-11
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公开(公告)号： EP2814840A1公开(公告)日： 2014-12-24
- 发明人: SCHELLENBERGER, Volker , CHANG, Pei-yun , VARFAJ, Fatbardha , DING, Sheng , SILVERMAN, Joshua , WANG, Chia-wei , SPINK, Benjamin , STEMMER, Willem, P. , GEETHING, Nathan , KULMAN, John , LIU, Tongyao , TOBY, Garabet, G. , JIANG, Haiyan , PETERS, Robert , WANG, Deping , MEI, Baisong
- 申请人： Amunix Operating Inc. , Biogen Idec MA Inc.
- 申请人地址： 500 Ellis Street Mountain View, CA 94043 US
- 专利权人： Amunix Operating Inc.,Biogen Idec MA Inc.
- 当前专利权人： Amunix Operating Inc.,Biogen Idec MA Inc.
- 当前专利权人地址： 500 Ellis Street Mountain View, CA 94043 US
- 代理机构： Miller, David James
- 优先权： US201261599400P 20120215
- 国际公布： WO2013122617 20130822
- 主分类号： C07K14/755
- IPC分类号： C07K14/755 ; A61K38/37
摘要：
The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
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