发明公开
- 专利标题: TNF -ALPHA MODULATING BENZIMIDAZOLES
- 专利标题(中): TNF-ALPHA-MODULIERENDE BENZIMIDAZOLE
-
申请号: EP13727932.9申请日: 2013-06-11
-
公开(公告)号: EP2858983A1公开(公告)日: 2015-04-15
- 发明人: BROOKINGS, Daniel, Christopher , CALMIANO, Mark, Daniel , GALLIMORE, Ellen, Olivia , HORSLEY, Helen, Tracey , HUTCHINGS, Martin, Clive , JOHNSON, James, Andrew , KROEPLIEN, Boris , LECOMTE, Fabien, Claude , LOWE, Martin, Alexander , NORMAN, Timothy, John , PORTER, John, Robert , QUINCEY, Joanna, Rachel , REUBERSON, James, Thomas , SELBY, Matthew, Duncan , SHAW, Michael, Alan , ZHU, Zhaoning , FOLEY, Anne Marie
- 申请人: UCB Biopharma SPRL
- 申请人地址: 60, Allee de la Recherche 1070 Brussels BE
- 专利权人: UCB Biopharma SPRL
- 当前专利权人: UCB Biopharma SPRL
- 当前专利权人地址: 60, Allee de la Recherche 1070 Brussels BE
- 代理机构: Duckworth, Timothy John
- 优先权: GB201210233 20120611; GB201221983 20121206
- 国际公布: WO2013186229 20131219
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; C07D235/12 ; A61K31/4427 ; A61P29/00
摘要:
A series of benzimidazole derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
公开/授权文献
- EP2858983B1 TNF-ALPHA MODULATING BENZIMIDAZOLES 公开/授权日:2018-04-18
信息查询