发明授权
- 专利标题： TNF-ALPHA MODULATING BENZIMIDAZOLES
- 专利标题（中）： TNF-α调节苯并咪唑
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申请号： EP13727932.9申请日： 2013-06-11
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公开(公告)号： EP2858983B1公开(公告)日： 2018-04-18
- 发明人: BROOKINGS, Daniel, Christopher , CALMIANO, Mark, Daniel , GALLIMORE, Ellen, Olivia , HORSLEY, Helen, Tracey , HUTCHINGS, Martin, Clive , JOHNSON, James, Andrew , KROEPLIEN, Boris , LECOMTE, Fabien, Claude , LOWE, Martin, Alexander , NORMAN, Timothy, John , PORTER, John, Robert , QUINCEY, Joanna, Rachel , REUBERSON, James, Thomas , SELBY, Matthew, Duncan , SHAW, Michael, Alan , ZHU, Zhaoning , FOLEY, Anne Marie
- 申请人： UCB Biopharma SPRL
- 申请人地址： 60, Allée de la Recherche 1070 Brussels BE
- 专利权人： UCB Biopharma SPRL
- 当前专利权人： UCB Biopharma SPRL
- 当前专利权人地址： 60, Allée de la Recherche 1070 Brussels BE
- 代理机构： J A Kemp
- 优先权： GB201210233 20120611; GB201221983 20121206
- 国际公布： WO2013186229 20131219
- 主分类号： C07D401/04
- IPC分类号： C07D401/04 ; C07D235/12 ; A61K31/4427 ; A61P29/00
摘要：
A series of benzimidazole derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
公开/授权文献
- EP2858983A1 TNF -ALPHA MODULATING BENZIMIDAZOLES 公开/授权日：2015-04-15
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