发明授权
EP3154973B1 TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
有权
作为α-7烟碱乙酰胆碱受体配体的三环化合物
- 专利标题： TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
- 专利标题（中）： 作为α-7烟碱乙酰胆碱受体配体的三环化合物
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申请号： EP15729057.8申请日： 2015-06-05
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公开(公告)号： EP3154973B1公开(公告)日： 2018-03-21
- 发明人: MCDONALD, Ivar M. , ZUSI, F. Christopher , OLSON, Richard E.
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： Route 206 and Province Line Road Princeton, NJ 08543 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： Route 206 and Province Line Road Princeton, NJ 08543 US
- 代理机构： Reitstötter Kinzebach
- 优先权： US201462011635P 20140613
- 国际公布： WO2015191403 20151217
- 主分类号： C07D471/18
- IPC分类号： C07D471/18 ; A61K31/4748 ; A61P25/00
摘要：
The disclosure provides compounds of formula I including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic 7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders. [INSERT CHEMICAL STRUCTURE HERE] I
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