Invention Publication
- Patent Title: BENZAMIDE DERIVATIVE AS HISTONE DEACETYLASE INHIBITOR WITH POTENT DIFFERENTIATION AND ANTI-PROLIFERATION ACTIVITY
-
Application No.: EP17200696.7Application Date: 2004-02-09
-
Publication No.: EP3336078A1Publication Date: 2018-06-20
- Inventor: Lu, Xian-Ping , Li, Zhibin , Xie, Aihua , Li, Boyu , Ning, Zhiqiang , Shan, Song , Deng, Tuo , Hu, Weiming , Shi, Leming
- Applicant: Shenzhen Chipscreen Biosciences Ltd.
- Applicant Address: Res. Inst. of Tsinghua Uni., Ste C301, P.O.Box 28, High-Tech Industrial Park, Nanshan District Shenzhen, Guangdong 518257 CN
- Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee: Shenzhen Chipscreen Biosciences Ltd.
- Current Assignee Address: Res. Inst. of Tsinghua Uni., Ste C301, P.O.Box 28, High-Tech Industrial Park, Nanshan District Shenzhen, Guangdong 518257 CN
- Agency: Rashid, Jeremy Suhail
- Priority: US447915P 20030214; US770035 20040202
- Main IPC: C07D213/56
- IPC: C07D213/56 ; C07C233/51 ; C07C237/42 ; A61K31/4406 ; A61K31/165 ; A61P17/06 ; A61P35/00
Abstract:
The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis.
Information query
