- 专利标题: UBIQUITIN VARIANTS AND USES THEREOF AS 53BP1 INHIBITORS
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申请号: EP17746656.2申请日: 2017-01-31
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公开(公告)号: EP3411391A1公开(公告)日: 2018-12-12
- 发明人: DUROCHER, Daniel , SIDHU, Sachdev , ZHANG, Wei , SICHERI, Frank , CANNY, Marella
- 申请人: The Governing Council Of The University Of Toronto , Sinai Health System
- 申请人地址: Banting Institute 100 College Street Toronto, ON M5G 1L5 CA
- 专利权人: The Governing Council Of The University Of Toronto,Sinai Health System
- 当前专利权人: The Governing Council Of The University Of Toronto,Sinai Health System
- 当前专利权人地址: Banting Institute 100 College Street Toronto, ON M5G 1L5 CA
- 代理机构: D Young & Co LLP
- 优先权: US201662289627P 20160201
- 国际公布: WO2017132746 20170810
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; A61K38/17 ; C12N15/00 ; C12N15/12
摘要:
53BP1 inhibitors, derived from the modification of wild-type ubiquitin, as well as compositions comprising the inhibitors and methods of using same are provided. The inhibitors can be used in combination with gene editing systems.
公开/授权文献
- EP3411391B1 UBIQUITIN VARIANTS AND USES THEREOF AS 53BP1 INHIBITORS 公开/授权日:2021-11-10
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