专利检索 ap:("The Governing Council Of The University Of Toronto" OR "Sinai Health System") AND inv:"CANNY, Marella" 第 1 页

1.

发明公开
UBIQUITIN VARIANTS AND USES THEREOF AS 53BP1 INHIBITORS 审中-公开

公开(公告)号：EP3411391A1

公开(公告)日：2018-12-12

申请号：EP17746656.2

申请日：2017-01-31

申请人： The Governing Council Of The University Of Toronto , Sinai Health System

发明人： DUROCHER, Daniel , SIDHU, Sachdev , ZHANG, Wei , SICHERI, Frank , CANNY, Marella

IPC分类号： C07K14/47 , A61K38/17 , C12N15/00 , C12N15/12

CPC分类号： C12N15/00 , A61K38/00 , C07K14/47

摘要： 53BP1 inhibitors, derived from the modification of wild-type ubiquitin, as well as compositions comprising the inhibitors and methods of using same are provided. The inhibitors can be used in combination with gene editing systems.