发明公开
- 专利标题： PROCESS FOR PREPARING 4-SUBSTITUTED-1-(2-METHOXYETHYL)PYRROLIDIN-3-AMINE DERIVATIVES
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申请号： EP19163878.2申请日： 2019-03-19
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公开(公告)号： EP3564236A1公开(公告)日： 2019-11-06
- 发明人: ALLEN, Shelley , ANDREWS, Steven W. , BAER, Brian , CRANE, Zackary , LIU, Weidong , WATSON, Daniel John
- 申请人： Array Biopharma, Inc.
- 申请人地址： 3200 Walnut Street Boulder, CO 80301 US
- 专利权人： Array Biopharma, Inc.
- 当前专利权人： Array Biopharma, Inc.
- 当前专利权人地址： 3200 Walnut Street Boulder, CO 80301 US
- 代理机构： Office Freylinger
- 优先权： US201461993426P 20140515
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D403/14 ; A61K31/4155 ; A61K45/06 ; A61K9/00 ; C07D207/16 ; A61K31/506
摘要：
Provided is Compound 1
or a pharmaceutically acceptable salt thereof, which is an inhibitor of TrkA kinase and is useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation and inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome, diseases related to an imbalance of the regulation of bone remodeling, and diseases resulting from Connective Tissue Growth Factor aberrant signaling.
or a pharmaceutically acceptable salt thereof, which is an inhibitor of TrkA kinase and is useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation and inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome, diseases related to an imbalance of the regulation of bone remodeling, and diseases resulting from Connective Tissue Growth Factor aberrant signaling.
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