发明公开
- 专利标题： NOVEL THIOPHOSPHORAMIDITES
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申请号： EP21215936.2申请日： 2018-12-21
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公开(公告)号： EP4092118A1公开(公告)日： 2022-11-23
- 发明人: BLEICHER, Konrad , DUSCHMALÉ, Joerg , DUSCHMALÉ, Martina Brigitte , HANSEN, Henrik Frydenlund , KOCH, Troels , LI, Meiling , SCHAEUBLIN, Adrian , SHU, Xi , WU, Yong
- 申请人： Roche Innovation Center Copenhagen A/S
- 申请人地址： DK 2970 Hørsholm Fremtidsvej 3
- 代理机构： Sauer, Frank
- 优先权： EP18198487 20181003
- 主分类号： C12N15/11
- IPC分类号： C12N15/11 ; C07F9/165 ; C07H19/10 ; C07H19/20 ; C07H21/00
摘要：
The present invention relates to a compound of formula (II) or (IIb)
wherein X, Y, R x , R y , R 5 and Nu are as defined in the description and in the claims. The compound of formula (II) can be used in the manufacture of oligonucleotides.
wherein X, Y, R x , R y , R 5 and Nu are as defined in the description and in the claims. The compound of formula (II) can be used in the manufacture of oligonucleotides.
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