- 专利标题: Compositions and methods for detecting EGFR in cancer
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申请号: US12450457申请日: 2009-04-10
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公开(公告)号: US10000568B2公开(公告)日: 2018-06-19
- 发明人: Ting-Lei Gu , Jiong Wu , Susan Kane , Jian Yu , Herbert Haack , James Wieler , Jun-Ming Cai , Victoria Rimkunas
- 申请人: Ting-Lei Gu , Jiong Wu , Susan Kane , Jian Yu , Herbert Haack , James Wieler , Jun-Ming Cai , Victoria Rimkunas
- 申请人地址: US MA Danvers
- 专利权人: Cell Signaling Technology, Inc.
- 当前专利权人: Cell Signaling Technology, Inc.
- 当前专利权人地址: US MA Danvers
- 代理机构: Scully Scott Murphy & Presser
- 国际申请: PCT/US2009/002247 WO 20090410
- 国际公布: WO2009/126306 WO 20091015
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; C07K16/28 ; C07K14/47 ; C07K14/485 ; G01N33/574
摘要:
The invention discloses binding agents to the E746-A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer.
公开/授权文献
- US20120093837A1 COMPOSITIONS AND METHODS FOR DETECTING EGFR IN CANCER 公开/授权日:2012-04-19