Methods and Apparatus for Multi-Stage VM Virtual Network Function and Virtual Service Function Chain Acceleration for NFV and needs-based hardware acceleration. Compute platform hosting virtualized environments including virtual machines (VMs) running service applications performing network function virtualization (NFV) employ Field Programmable Gate Array (FPGA) to provide a hardware-based fast path for performing VM-to-VM and NFV-to-NFV transfers. The FPGAs, along with associated configuration data are also configured to support dynamic assignment and performance of hardware-acceleration to offload processing tasks from processors in virtualized environments, such as cloud data centers and the like.