The invention of the current application is a process for eliminating arsenic from a hydrocarbon feed which is at least partially liquid, including steps a and b.Step a includes bringing the hydrocarbon feed and hydrogen into contact with a first capture mass including a support and at least one metal M1 from group VIB and at least two metals M2 and M3 from group VIII.Step b includes bringing the hydrocarbon feed and hydrogen into contact with a second capture mass in the sulphide form including a support and nickel, the quantity of nickel being at least 5% by weight of NiO with respect to the total weight of the second capture mass.Step a) is either carried out before step b) or carried out simultaneously with step b).