- 专利标题： Modified relaxin B chain peptides
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申请号： US15304434申请日： 2015-04-17
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公开(公告)号： US10081662B2公开(公告)日： 2018-09-25
- 发明人: Ross Alexander David Bathgate , Mohammed Akhter Hossain , John Desmond Wade
- 申请人： The Florey Institute of Neuroscience and Mental Health
- 申请人地址： AU Parkville, Victoria
- 专利权人： THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH
- 当前专利权人： THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH
- 当前专利权人地址： AU Parkville, Victoria
- 代理机构： Blank Rome LLP
- 优先权： AU2014901409 20140417
- 国际申请： PCT/AU2015/050184 WO 20150417
- 国际公布： WO2015/157829 WO 20151022
- 主分类号： C07K14/00
- IPC分类号： C07K14/00 ; C07K14/435 ; C07K14/46 ; C07K14/47 ; C07K14/575 ; C07K14/64 ; C12N15/00 ; C12N15/09 ; C12N15/11 ; C12N15/12 ; C12N15/16 ; A61K38/00
摘要：
Provided herein are biologically active single chain relaxin peptides. In particular the present invention relates to single chain relaxin peptides comprising a B chain derived from relaxin-2, the peptide being truncated by one or more amino acid residues at the N-terminus with respect to the sequence of the B chain of native relaxin-2. Typically the single chain relaxin peptides selectively bind to the RXFP1 receptor.
公开/授权文献
- US20170037106A1 MODIFIED RELAXIN B CHAIN PEPTIDES 公开/授权日：2017-02-09
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