专利检索 ap:("The Florey Institute of Neuroscience AND Mental Health") AND inv:"Mohammed Akhter Hossain" 第 1 页

1.

发明授权
Modified relaxin B chain peptides 有权

公开(公告)号：US10081662B2

公开(公告)日：2018-09-25

申请号：US15304434

申请日：2015-04-17

申请人： The Florey Institute of Neuroscience and Mental Health

发明人： Ross Alexander David Bathgate , Mohammed Akhter Hossain , John Desmond Wade

IPC分类号： C07K14/00 , C07K14/435 , C07K14/46 , C07K14/47 , C07K14/575 , C07K14/64 , C12N15/00 , C12N15/09 , C12N15/11 , C12N15/12 , C12N15/16 , A61K38/00

CPC分类号： C07K14/64 , A61K38/00

摘要： Provided herein are biologically active single chain relaxin peptides. In particular the present invention relates to single chain relaxin peptides comprising a B chain derived from relaxin-2, the peptide being truncated by one or more amino acid residues at the N-terminus with respect to the sequence of the B chain of native relaxin-2. Typically the single chain relaxin peptides selectively bind to the RXFP1 receptor.