Invention Grant
- Patent Title: NAMPT and ROCK inhibitors
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Application No.: US14880834Application Date: 2015-10-12
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Publication No.: US10093624B2Publication Date: 2018-10-09
- Inventor: Rick F. Clark , Michael L. Curtain , Todd M. Hansen , Howard R. Heyman , Helmut Mack , Michael Michaelides , Marina A. Pliushchev , Omar J. Shah , Bryan K. Sorensen , Ramzi Sweis , Chris Tse , Anil Vasudevan , Kevin R. Woller
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agent Glen Gesicki
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D209/44 ; C07D401/12 ; C07D401/14 ; C07D403/10 ; C07D403/12 ; C07D403/14 ; C07D405/12 ; C07D407/12 ; C07D407/14 ; C07D413/12 ; C07D417/12 ; C07D471/04 ; C07D491/048 ; C07D495/04 ; A61K31/437 ; A61K31/496 ; A61K31/4985 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; C07D519/00
Abstract:
Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.
Public/Granted literature
- US20160031880A1 Nampt and Rock Inhibitors Public/Granted day:2016-02-04
Information query
IPC分类:
