-
公开(公告)号：US20170065575A1
公开(公告)日：2017-03-09
申请号：US15357383
申请日：2016-11-21
Applicant: AbbVie Inc.
Inventor： Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: A61K31/4545 , A61K31/506 , A61K31/501 , A61K31/5377 , A61K31/496
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
Abstract translation: 公开了抑制NAMPT活性的化合物，含有该化合物的组合物和治疗其中NAMPT表达的疾病的方法。
-
公开(公告)号：US10053474B2
公开(公告)日：2018-08-21
申请号：US15588037
申请日：2017-05-05
Applicant: AbbVie Inc.
Inventor： Jaclyn Chau , Hui-Ju J. Chen , David A. DeGoey , John Hartung , Nathan Ide , Vikram Kalthod , Allan C. Krueger , Yi-Yin Ku , Tongmei Li , John T. Randolph , Rolf Wagner , Geoff T. Halvorsen , Christopher C. Marvin , Eric Voight , Brian S. Brown , Steven R. Martinez , Anurupa Shrestha , Howard R. Heyman
IPC: A61K31/675 , C07F9/02 , C07F9/08 , C07F9/6512 , C07H19/10
CPC classification number: C07F9/08 , C07F9/6512 , C07H19/10
Abstract: The present invention features compounds effective in inhibiting active against Hepatitis C virus (“HCV”) polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
-
公开(公告)号：US09758511B2
公开(公告)日：2017-09-12
申请号：US15048574
申请日：2016-02-19
Applicant: AbbVie Inc.
Inventor： Michael L. Curtin , Kenton Longenecker , Todd M. Hansen , Richard F. Clark , Bryan Sorensen , Howard R. Heyman , Zhiqin Ji
IPC: C07D401/14 , C07D405/14 , C07D409/14 , C07D417/14 , A61K45/06
CPC classification number: C07D405/14 , A61K45/06 , C07D401/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US20170135994A9
公开(公告)日：2017-05-18
申请号：US14878858
申请日：2015-10-08
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/496
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US20160184282A1
公开(公告)日：2016-06-30
申请号：US14878858
申请日：2015-10-08
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael Michaelides , Ramzi Sweis , Marina Pliushchev , Andrew Judd , Todd Hansen , Howard R. Heyman
IPC: A61K31/437 , A61K31/4545 , A61K31/496
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
Patent Agency Ranking
公开(公告)号：US08975398B2
公开(公告)日：2015-03-10
申请号：US13891357
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: C07D401/00 , C07D405/14 , A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/5377 , C07D409/14 , C07D417/14 , A61K31/506 , C07D401/14 , C07D401/04 , C07D403/04 , C07D403/14
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US20130303511A1
公开(公告)日：2013-11-14
申请号：US13891366
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K45/06 , C07D487/04 , A61K31/4985 , A61K31/437 , A61K31/5377
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US20130303509A1
公开(公告)日：2013-11-14
申请号：US13891354
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Todd M. Hansen , Kenton Longenecker , Howard R. Heyman , Michael L. Curtin , Richard F. Clark , Bryan Sorensen , Zhiqin Ji , Kevin Woller , George Doherty , Robin Frey
IPC: C07D405/14 , C07D409/14 , A61K31/501 , C07D417/14 , A61K31/496 , A61K31/4545 , A61K31/5377
CPC classification number: A61K31/4545 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US20130303508A1
公开(公告)日：2013-11-14
申请号：US13891349
申请日：2013-05-10
Applicant: AbbVie Inc.
Inventor： Richard F. Clark , Bryan Sorensen , Augustine T. Osuma , Robin Frey , Kenton Longenecker , George Doherty , Michael L. Curtin , Michael R. Michaelides , Ramzi F. Sweis , Marina A. Pliushchev , Andy Judd , Todd M. Hansen , Howard R. Heyman
IPC: C07D471/04 , A61K31/5377 , A61K45/06 , A61K31/496 , A61K31/55 , A61K31/4725 , A61K31/437 , A61K31/4545
CPC classification number: A61K31/437 , A61K31/407 , A61K31/444 , A61K31/4545 , A61K31/4725 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D471/04 , C07D487/04 , A61K2300/00
Abstract: Disclosed are compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed.
-
公开(公告)号：US10093624B2
公开(公告)日：2018-10-09
申请号：US14880834
申请日：2015-10-12
Applicant: AbbVie Inc.
Inventor： Rick F. Clark , Michael L. Curtain , Todd M. Hansen , Howard R. Heyman , Helmut Mack , Michael Michaelides , Marina A. Pliushchev , Omar J. Shah , Bryan K. Sorensen , Ramzi Sweis , Chris Tse , Anil Vasudevan , Kevin R. Woller
IPC: A01N43/42 , A61K31/44 , C07D209/44 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/12 , C07D407/12 , C07D407/14 , C07D413/12 , C07D417/12 , C07D471/04 , C07D491/048 , C07D495/04 , A61K31/437 , A61K31/496 , A61K31/4985 , A61K31/501 , A61K31/506 , A61K31/5377 , C07D519/00
Abstract: Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of NAMPT, compositions containing the compounds and methods of treating diseases during which NAMPT is expressed. Disclosed are isoindoline carboxamide, dihydropyrrolopyridine carboxamide, and dihydropyrrolopyrimidine carboxamide compounds which inhibit the activity of ROCK, compositions containing the compounds and methods of treating diseases during which ROCK is expressed.
-
-
-
-
-
-
-
-
-
Search Results
20
records
(took 0.062 seconds)
