Invention Grant
- Patent Title: Production of virus-receptive pluripotent stem cell (PSC)-derived hepatocytes
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Application No.: US15297420Application Date: 2016-10-19
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Publication No.: US10093903B2Publication Date: 2018-10-09
- Inventor: Christian Kannemeier , Elisabeth Enghofer , Lisa Harms
- Applicant: FUJIFILM Cellular Dynamics, Inc.
- Applicant Address: US WI Madison
- Assignee: FUJIFILM Cellular Dynamics, Inc.
- Current Assignee: FUJIFILM Cellular Dynamics, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/074 ; C12N15/85 ; C07H21/04 ; A01K67/00 ; C12N5/071 ; G01N33/50
Abstract:
The present disclosure provides methods for maturing hepatocytes comprising culturing with cyclic adenosine monophosphate and a Janus kinase inhibitor. There is also provided a method for screening inhibitors of hepatitis B virus infection and/or replication.
Public/Granted literature
- US20170107485A1 PRODUCTION OF VIRUS-RECEPTIVE PLURIPOTENT STEM CELL (PSC)-DERIVED HEPATOCYTES Public/Granted day:2017-04-20
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