Invention Grant
- Patent Title: Red blood cell lysis solution
-
Application No.: US14918131Application Date: 2015-10-20
-
Publication No.: US10093989B2Publication Date: 2018-10-09
- Inventor: Jijumon Chelliserry , Kui Gao , Jeffrey M. Linnen
- Applicant: Gen-Probe Incorporated
- Applicant Address: US CA San Diego
- Assignee: GEN-PROBE INCORPORATED
- Current Assignee: GEN-PROBE INCORPORATED
- Current Assignee Address: US CA San Diego
- Agent Jeffrey E. Landes; Nicholas V. Sherbina
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6893 ; C12N1/06 ; G01N33/48

Abstract:
The invention provides a lysis reagent for lysing red blood cells, thereby releasing a target, such as RNA from a parasitic organism, in a form suitable for analysis. The reagent includes at least ammonium chloride and an anionic detergent, and may include an anti-coagulant. The reagent serves to lyse red blood cells, protect the released target from degradation in the lysate, and is compatible with subsequent steps for analysis of the target such as target capture, amplification, detection, or sequencing.
Public/Granted literature
- US20160201144A1 RED BLOOD CELL LYSIS SOLUTION Public/Granted day:2016-07-14
Information query