A method of indoor positioning using Fine Timing Measurement (FTM) protocol with multi-antenna access point (AP) is proposed. In a wireless local area network, an AP has multiple antennas that are strategically located in different physical locations. The AP is used to exchange FTM frames with a wireless station for timing measurement of the FTM frames via its multiple antennas independently. The timing measurement result (e.g., timestamps of transmitting and receiving FTM frames) is then used to determine an absolute location of the station. A simplified Indoor Location operation with simplified deployment is achieved.