Invention Grant
- Patent Title: Glucosylceramide synthase inhibitors and therapeutic methods using the same
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Application No.: US15546320Application Date: 2016-02-01
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Publication No.: US10202340B2Publication Date: 2019-02-12
- Inventor: Scott D. Larsen , Akira Abe , Liming Shu , Michael William Wilson , Richard F. Keep , Duxin Sun , James A. Shayman
- Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Applicant Address: US MI Ann Arbor
- Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2016/015883 WO 20160201
- International Announcement: WO2016/126572 WO 20160811
- Main IPC: A61K31/4015
- IPC: A61K31/4015 ; C07D207/06 ; C07D263/20 ; C07D207/04 ; C07D263/24 ; C07D205/04 ; C07D207/09 ; C07D207/10 ; C07D295/125 ; C07D295/13
Abstract:
Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.
Public/Granted literature
- US20180022697A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS AND THERAPEUTIC METHODS USING THE SAME Public/Granted day:2018-01-25
Information query
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