Invention Grant
- Patent Title: Method and device for identifying nucleotide, and method and device for determining nucleotide sequence of polynucleotide
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Application No.: US14883494Application Date: 2015-10-14
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Publication No.: US10202644B2Publication Date: 2019-02-12
- Inventor: Masateru Taniguchi , Makusu Tsutsui , Kazumichi Yokota , Tomoji Kawai
- Applicant: Quantum Biosystems Inc.
- Applicant Address: JP Tokyo
- Assignee: QUANTUM BIOSYSTEMS INC.
- Current Assignee: QUANTUM BIOSYSTEMS INC.
- Current Assignee Address: JP Tokyo
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12Q1/6874
- IPC: C12Q1/6874 ; G01N27/327 ; C12Q1/6869
Abstract:
The present invention provides technology that uses current measurements to identify nucleotides and determine a nucleotide sequence in polynucleotides. The present invention calculates a modal value of a tunnel current that arises when a nucleotide or polynucleotide for analysis passes through between electrodes, and then employs the calculated modal value. The present invention accordingly enables direct rapid implementation to identify nucleotides and to determine a nucleotide sequence in a polynucleotide without marking.
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