公开(公告)号：US10202644B2

公开(公告)日：2019-02-12

申请号：US14883494

申请日：2015-10-14

Applicant: Quantum Biosystems Inc.

Inventor： Masateru Taniguchi ,  Makusu Tsutsui ,  Kazumichi Yokota ,  Tomoji Kawai

IPC: C12Q1/6874 ,  G01N27/327 ,  C12Q1/6869

Abstract: The present invention provides technology that uses current measurements to identify nucleotides and determine a nucleotide sequence in polynucleotides. The present invention calculates a modal value of a tunnel current that arises when a nucleotide or polynucleotide for analysis passes through between electrodes, and then employs the calculated modal value. The present invention accordingly enables direct rapid implementation to identify nucleotides and to determine a nucleotide sequence in a polynucleotide without marking.

公开(公告)号：US20190242846A1

公开(公告)日：2019-08-08

申请号：US16266363

申请日：2019-02-04

Applicant: Quantum Biosystems Inc. ,  Osaka University

Inventor： Masateru TANIGUCHI ,  Takahito Ohshiro ,  Makusu Tsutsui ,  Kazumichi Yokota ,  Toshiki Matsuoka ,  Mark Oldham ,  Eric Nordman

IPC: G01N27/327 ,  G01N33/487

CPC classification number: G01N27/3278 ,  B82Y40/00 ,  C12M1/00 ,  C12Q1/6869 ,  G01N33/48721

Abstract: Methods and systems are provided for creation of stable and consistent nanoelectrode pairs for detection of biomolecules, such as deoxyribonucleic acid.