Invention Grant
- Patent Title: Modified kappa light chain-binding polypeptides
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Application No.: US15526895Application Date: 2015-12-11
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Publication No.: US10208092B2Publication Date: 2019-02-19
- Inventor: Gustav Rodrigo , Mats Ander , Tomas Bjorkman
- Applicant: GE HEALTHCARE BIOPROCESS R&D AB
- Applicant Address: SE Uppsala
- Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: SE1451563 20141217; SE1451564 20141217
- International Application: PCT/EP2015/079389 WO 20151211
- International Announcement: WO2016/096644 WO 20160623
- Main IPC: C07K14/195
- IPC: C07K14/195 ; C07K1/22 ; C07K16/00

Abstract:
The invention discloses kappa light chain-binding polypeptide comprising a mutated binding domain of Peptostreptococcus protein L, wherein at least one asparagine residue of a parental domain defined by, or having at least 95% or 98% sequence homology with, SEQ ID NO: 2-6 or 2 has been mutated to another amino acid residue which is not asparagine, proline or cysteine.
Public/Granted literature
- US20170320919A1 Modified Kappa Light Chain-Binding Polypeptides Public/Granted day:2017-11-09
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