Invention Grant
- Patent Title: Nucleic acids encoding bispecific antibodies binding to beta-Klotho and fibroblast growth factor receptor 1
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Application No.: US15837801Application Date: 2017-12-11
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Publication No.: US10246518B2Publication Date: 2019-04-02
- Inventor: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Baker Botts L.L.P.
- Main IPC: C12N15/13
- IPC: C12N15/13 ; C07K16/40 ; C07K14/71 ; C07K16/28 ; A61K39/00
Abstract:
The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
Public/Granted literature
- US20180105605A1 ANTIBODIES AND METHODS OF USE Public/Granted day:2018-04-19
Information query
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