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公开(公告)号:US20140314763A1
公开(公告)日:2014-10-23
申请号:US14148414
申请日:2014-01-06
申请人: Genentech, Inc.
发明人: Yongmei Chen , Yan (Helen) Hu , Wenjun Ouyang , Scott Stawicki , Yan Wu
IPC分类号: C07K16/24
CPC分类号: C07K16/244 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要: The present invention relates generally to antibodies cross-reactive with IL-17A and IL-17F, and bispecific anti-IL-17A/F and their uses.
摘要翻译: 本发明一般涉及与IL-17A和IL-17F交叉反应的抗体,以及双特异性抗IL-17A / F及其用途。
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公开(公告)号:US10882921B2
公开(公告)日:2021-01-05
申请号:US16284774
申请日:2019-02-25
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US20180105605A1
公开(公告)日:2018-04-19
申请号:US15837801
申请日:2017-12-11
申请人: Genentech, Inc.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC分类号: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US20150218276A1
公开(公告)日:2015-08-06
申请号:US14582100
申请日:2014-12-23
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
IPC分类号: C07K16/28
CPC分类号: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
摘要翻译: 目前公开的主题提供了结合KLB和FGFR1的抗体及其使用方法。 在某些实施方案中,本公开的抗体包括结合存在于FGFR1上并与KLB上存在的表位结合的双特异性抗体。
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公开(公告)号:US20220064331A1
公开(公告)日:2022-03-03
申请号:US17341990
申请日:2021-06-08
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US20190177432A1
公开(公告)日:2019-06-13
申请号:US16284774
申请日:2019-02-25
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US10246518B2
公开(公告)日:2019-04-02
申请号:US15837801
申请日:2017-12-11
申请人: Genentech, Inc.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US20190016826A1
公开(公告)日:2019-01-17
申请号:US16143098
申请日:2018-09-26
申请人: Genentech, Inc.
发明人: Yan Wu , Menno van Lookeren Campagne , Daniel Kirchhofer , Michael Terry Lipari , Kenneth J. Katschke, JR. , Paul M. Moran , Scott Stawicki , Wei-Ching Liang
IPC分类号: C07K16/40
摘要: The invention provides anti-HtrA1 antibodies and methods of using the same.
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公开(公告)号:US09884919B2
公开(公告)日:2018-02-06
申请号:US15214160
申请日:2016-07-19
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
IPC分类号: A61K39/395 , C07K16/40 , C07K14/71 , C07K16/28 , A61K39/00
CPC分类号: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号:US09873748B2
公开(公告)日:2018-01-23
申请号:US14582100
申请日:2014-12-23
申请人: GENENTECH, INC.
发明人: Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC分类号: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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