Invention Grant
- Patent Title: Chromatography method
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Application No.: US15308327Application Date: 2015-06-04
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Publication No.: US10266563B2Publication Date: 2019-04-23
- Inventor: Jean-Luc Maloisel , Ola Lind , Bjorn Noren , Ronnie Palmgren
- Applicant: GE Healthcare BioProcess R&D AB
- Applicant Address: SE Uppsala
- Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Wood IP LLC
- Priority: SE1450779 20140624
- International Application: PCT/EP2015/062500 WO 20150604
- International Announcement: WO2015/197338 WO 20151230
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K16/00 ; C07K16/06 ; C07K1/14

Abstract:
The present invention relates to a method for removal of large contaminants, such as virus, in a chromatographic process for purification of a target molecule, preferably monoclonal antibodies, mAbs, by using a specifically designed chromatographic bead having a thin outer layer and a core functionalized with a ligand adsorbing the mAbs or parts thereof.
Public/Granted literature
- US20170051010A1 CHROMATOGRAPHY METHOD Public/Granted day:2017-02-23
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