Invention Grant
- Patent Title: Exonuclease deficient polymerases
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Application No.: US15444020Application Date: 2017-02-27
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Publication No.: US10266813B2Publication Date: 2019-04-23
- Inventor: Aruna Ayer , Arkadiusz Bibillo , Preethi Sarvabhowman , Dhruti Vasudev Dalal , Ilya Lederman , Eileen Thai
- Applicant: Genia Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Genia Technologies, Inc.
- Current Assignee: Genia Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Roche Molecular Systems, Inc.
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12N15/00 ; C07H21/04

Abstract:
Described herein are polymerase variants that are exonuclease deficient. Some variants retain the strand displacement capability comparable to the wild-type or parental polymerase. Some variants have a strand displacement capability that is improved relative to the wild-type or parental polymerase. The variants may have an extension rate that is greater than the wild-type or parental polymerase. The variants may have a waiting time that is less than the wild-type or parental polymerase.
Public/Granted literature
- US20170267983A1 Exonuclease Deficient Polymerases Public/Granted day:2017-09-21
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