Invention Grant
- Patent Title: Hepatitis B viral assembly effectors
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Application No.: US15566633Application Date: 2016-04-15
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Publication No.: US10273228B2Publication Date: 2019-04-30
- Inventor: Lee Daniel Arnold , Hans Maag , William W. Turner, Jr.
- Applicant: Indiana University Research and Technology Corporation
- Applicant Address: US IN Indianapolis US IN Carmel
- Assignee: Indiana University Research and Technology Corporation,Assembly Biosciences, Inc.
- Current Assignee: Indiana University Research and Technology Corporation,Assembly Biosciences, Inc.
- Current Assignee Address: US IN Indianapolis US IN Carmel
- Agency: Faegre Baker Daniels LLP
- International Application: PCT/US2016/027780 WO 20160415
- International Announcement: WO2016/168619 WO 20161020
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D401/04 ; C07D403/12 ; C07D401/12 ; C07D403/04 ; C07D239/42 ; C07D239/48 ; C07D409/12 ; C07D417/04 ; C07D417/12 ; C07D401/14 ; C07D417/14 ; C07D213/74 ; C07D239/47 ; C07D413/04 ; A61K31/496 ; A61K31/506 ; A61P31/20
Abstract:
Novel assembly effector compounds having a therapeutic effect against hepatitis B viral (HBV) infection are disclosed. Assembly effector molecules described herein can lead to defective viral assembly and also may affect other viral activities associated with chronic HBV infection. Also disclosed is a process to synthesize disclosed compounds, method of treatment of HBV by administration of disclosed compounds, and use of these compounds in the manufacture of medicaments against HBV.
Public/Granted literature
- US20180099952A1 HEPATITIS B VIRAL ASSEMBLY EFFECTORS Public/Granted day:2018-04-12
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