- 专利标题： Peptide inhibitors of serotonin 5-HT2C receptor:PTEN interaction
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申请号： US15450738申请日： 2017-03-06
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公开(公告)号： US10293022B2公开(公告)日： 2019-05-21
- 发明人: Kathryn Cunningham , Scott Gilbertson
- 申请人： Kathryn Cunningham , Scott Gilbertson
- 申请人地址： US TX Austin US TX Houston
- 专利权人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYTEM,THE UNIVERSITY OF HOUSTON SYSTEM
- 当前专利权人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYTEM,THE UNIVERSITY OF HOUSTON SYSTEM
- 当前专利权人地址： US TX Austin US TX Houston
- 代理机构： Norton Rose Fulbright US LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K39/00 ; A61K39/40 ; A01N37/18 ; A61K38/08 ; C07K7/06
摘要：
The inventors have identified how the assembly of the 5-HT2cR with another protein (phosphatase and tensin homologue; PTEN) controls cellular function, and have synthesized a new peptide that interrupts the 5-HT2cR:PTEN complex to result in enhanced 5-HT2cR function.
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