System and method embodiments are provided for interference alignment in a wireless local area network (LAN) with an overlapping basic service set (OBSS). In an embodiment, a method includes instructing a first access point (AP) in the wireless LAN to broadcast a null data packet (NDP) sounding packet to a plurality of stations when no other AP is broadcasting, wherein the NDP sounding packet comprises a plurality of long training field (LTFs), and wherein a total number of LTFs is equal to a total number of transmission streams, receiving channel beamforming (BF) information and a signal plus interference to noise ratio (SINR) from each of the stations, wherein each of the stations computes the channel BF information and the SINR from sounding packets received from each of the APs in the wireless LAN, and determining a transmission schedule according to the SINRs and the channel BF information.