Invention Grant
- Patent Title: Consumable cryopreserved cells transiently overexpressing gene(s) encoding drug transporter protein(s) and/or drug metabolizing enzyme(s)
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Application No.: US15988802Application Date: 2018-05-24
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Publication No.: US10336805B2Publication Date: 2019-07-02
- Inventor: Na Li , Jie Wang , Christopher J. Patten
- Applicant: Corning Incorporated
- Applicant Address: US NY Corning
- Assignee: Corning Incorporated
- Current Assignee: Corning Incorporated
- Current Assignee Address: US NY Corning
- Agency: Dinsmore & Shohl LLP
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/00 ; C12N5/02 ; C07K14/705 ; C12N15/85 ; A01N1/02 ; G01N33/50
Abstract:
The present invention discloses cryopreserved recombinant cells for screening drug candidates that transiently overexpress one or more drug transporter proteins and/or drug metabolizing enzymes. Advantageously, such cells provide a cost-efficient consumable product that streamlines the process of screening whether drug candidates are substrates or inhibitors of drug transporter proteins and/or drug metabolizing enzymes.
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