Invention Grant
- Patent Title: Hepatitis B core protein modulators
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Application No.: US15760284Application Date: 2016-09-15
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Publication No.: US10377748B2Publication Date: 2019-08-13
- Inventor: William Turner , Lee Daniel Arnold , Hans Maag , Leping Li , Mark Bures , Simon Haydar , Samson Francis
- Applicant: Assembly Biosciences, Inc. , INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
- Applicant Address: US IN Carmel US IN Indianapolis
- Assignee: Assembly Biosciences, Inc.,Indiana University Research And Technology Corporation
- Current Assignee: Assembly Biosciences, Inc.,Indiana University Research And Technology Corporation
- Current Assignee Address: US IN Carmel US IN Indianapolis
- Agency: Goodwin Procter LLP
- International Application: PCT/US2016/051934 WO 20160915
- International Announcement: WO2017/048950 WO 20170323
- Main IPC: C07D417/12
- IPC: C07D417/12 ; A61P31/20 ; C07D403/12 ; A61K45/06 ; C07D401/12 ; C07D413/12 ; C07D417/14 ; C07D453/02 ; C07D471/04 ; C07D243/38 ; C07D267/20 ; C07D281/16

Abstract:
The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
Public/Granted literature
- US20180258084A1 HEPATITIS B CORE PROTEIN MODULATORS Public/Granted day:2018-09-13
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