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公开(公告)号:US20230044112A1
公开(公告)日:2023-02-09
申请号:US17140800
申请日:2021-01-04
发明人: William W. Turner, JR. , Lee D. Arnold , Hans Maag , Leping Li , Mark G. Bures , Simon Nicolas Haydar , Samson Francis
IPC分类号: C07D417/12 , C07D403/12 , A61K45/06 , C07D401/12 , C07D413/12 , C07D417/14 , C07D453/02 , C07D471/04 , A61P31/20 , C07D243/38 , C07D267/20 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US20230019129A1
公开(公告)日:2023-01-19
申请号:US17154721
申请日:2021-01-21
IPC分类号: C07D417/12 , C07D403/12 , C07D223/20 , C07D401/12 , C07D413/12 , C07D243/38 , C07D281/14 , A61P31/12 , A61K31/55 , A61K31/5513 , A61K31/553 , A61K31/554 , A61K45/06 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10377748B2
公开(公告)日:2019-08-13
申请号:US15760284
申请日:2016-09-15
发明人: William Turner , Lee Daniel Arnold , Hans Maag , Leping Li , Mark Bures , Simon Haydar , Samson Francis
IPC分类号: C07D417/12 , A61P31/20 , C07D403/12 , A61K45/06 , C07D401/12 , C07D413/12 , C07D417/14 , C07D453/02 , C07D471/04 , C07D243/38 , C07D267/20 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10183936B2
公开(公告)日:2019-01-22
申请号:US15125911
申请日:2015-03-13
IPC分类号: C07D417/12 , C07D403/12 , C07D223/20 , C07D401/12 , C07D413/12 , C07D243/38 , C07D281/14 , A61K31/55 , A61K31/5513 , A61K31/553 , A61K31/554 , A61K45/06 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10968211B2
公开(公告)日:2021-04-06
申请号:US16426727
申请日:2019-05-30
发明人: William W. Turner, Jr. , Lee D. Arnold , Hans Maag , Leping Li , Mark G. Bures , Simon Nicolas Haydar , Samson Francis
IPC分类号: C07D417/12 , C07D403/12 , A61K45/06 , C07D401/12 , C07D413/12 , C07D417/14 , C07D453/02 , C07D471/04 , A61P31/20 , C07D243/38 , C07D267/20 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10947224B2
公开(公告)日:2021-03-16
申请号:US15965655
申请日:2018-04-27
IPC分类号: A61P31/12 , C07D417/12 , C07D403/12 , C07D223/20 , C07D401/12 , C07D413/12 , C07D243/38 , C07D281/14 , A61K31/55 , A61K31/5513 , A61K31/553 , A61K31/554 , A61K45/06 , C07D281/16
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10766890B2
公开(公告)日:2020-09-08
申请号:US15760387
申请日:2016-09-15
发明人: William Turner , Hans Maag , Samson Francis
IPC分类号: C07D417/12 , A61P31/20 , C07D281/16 , C07D403/12 , A61K45/06 , C07D401/12 , C07D413/12 , C07D417/14 , C07D453/02 , C07D471/04 , C07D243/38 , C07D267/20
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US10392379B2
公开(公告)日:2019-08-27
申请号:US15760343
申请日:2016-09-15
发明人: William Turner , Lee Daniel Arnold , Hans Maag , Mark Bures
IPC分类号: C07D243/38 , C07D267/20 , C07D281/16 , C07D401/12 , C07D403/12 , C07D417/12 , C07D417/14 , C07D453/02 , C07D471/04 , A61K45/06 , A61P31/20 , C07D413/12
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US20180258084A1
公开(公告)日:2018-09-13
申请号:US15760284
申请日:2016-09-15
发明人: William Turner , Lee Daniel Arnold , Hans Maag , Leping Li , Mark Bures , Simon Haydar , Samson Francis
IPC分类号: C07D417/12 , C07D417/14 , C07D453/02 , C07D471/04
CPC分类号: C07D417/12 , A61K45/06 , A61P31/20 , C07D243/38 , C07D267/20 , C07D281/16 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/14 , C07D453/02 , C07D471/04
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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公开(公告)号:US20180273521A1
公开(公告)日:2018-09-27
申请号:US15965655
申请日:2018-04-27
IPC分类号: C07D417/12 , C07D281/14 , A61K45/06 , C07D281/16 , A61K31/554 , C07D401/12 , A61K31/5513 , A61K31/553 , C07D413/12 , C07D223/20 , C07D403/12 , A61K31/55 , C07D243/38
摘要: The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.
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