Invention Grant
- Patent Title: Methods for reducing norleucine misincorporation into proteins using a microorganism comprising a mutant metA allele
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Application No.: US15951895Application Date: 2018-04-12
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Publication No.: US10421984B2Publication Date: 2019-09-24
- Inventor: Michael W. Laird , Karthik Veeravalli
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison and Foerster LLP
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12P21/02 ; C12N15/70 ; C12N9/10 ; C07K16/18 ; C07K16/22 ; C07K16/40 ; C07K16/28 ; C07K16/32
Abstract:
The present invention relates to methods and compositions for preventing incorporation of norleucine into proteins during recombinant protein production in bacteria. The present invention also provides microorganism host cells and nucleic acid molecules for use with the methods and compositions provided herein.
Public/Granted literature
- US20180230506A1 METHODS AND COMPOSITIONS FOR PREVENTING NORLEUCINE MISINCORPORATION INTO PROTEINS Public/Granted day:2018-08-16
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