Invention Grant
- Patent Title: Process for the preparation of isoxazoline compounds
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Application No.: US15480316Application Date: 2017-04-05
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Publication No.: US10433552B2Publication Date: 2019-10-08
- Inventor: Chunhua Yang , Loic Patrick Le Hir de Fallois , Charles Q. Meng , Alan Long , Roelof Johannes Gorter de Vries , Bruno Baillon , Sylvaine Lafont , Myriam Gay de Saint Michel , Stephane Kozlovic
- Applicant: MERIAL INC.
- Applicant Address: US GA Duluth
- Assignee: MERIAL, INC.
- Current Assignee: MERIAL, INC.
- Current Assignee Address: US GA Duluth
- Agency: Merial, Inc.
- Agent Judy Jarecki-Black; John Ezcurra
- Main IPC: C07D453/04
- IPC: C07D453/04 ; A01N43/80 ; C07D261/04 ; A01N43/42 ; A61K31/42

Abstract:
This invention relates to processes for the preparation of antiparasitic isoxazoline compounds enriched in an enantiomer using quinine-based chiral phase transfer catalyst. The invention also relates to novel quinine-based phase transfer catalysts and to a toluene solvent form of the isoxazoline compound of the invention.
Public/Granted literature
- US20170311601A1 PROCESS FOR THE PREPARATION OF ISOXAZOLINE COMPOUNDS Public/Granted day:2017-11-02
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