- 专利标题： Treatment of delta-like 1 homolog (DLK1) related diseases by inhibition of natural antisense transcript to DLK1
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申请号： US15804445申请日： 2017-11-06
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公开(公告)号： US10465192B2公开(公告)日： 2019-11-05
- 发明人: Joseph Collard , Olga Khorkova Sherman , Carlos Coito
- 申请人： CuRNA, Inc.
- 申请人地址： US FL Miami
- 专利权人： CuRNA, Inc.
- 当前专利权人： CuRNA, Inc.
- 当前专利权人地址： US FL Miami
- 代理机构： CuRNA, Inc.
- 代理商 Monte R. Browder
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C12N5/00
摘要：
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Delta-like 1 homolog (DLK1), in particular, by targeting natural antisense polynucleotides of Delta-like 1 homolog (DLK1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of DLK1.
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