Invention Grant
- Patent Title: Methods of increasing protein purity using protein A based chromatography
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Application No.: US14768254Application Date: 2014-03-07
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Publication No.: US10472389B2Publication Date: 2019-11-12
- Inventor: Nanying Bian , Melissa Holstein
- Applicant: EMD Millipore Corporation
- Applicant Address: US MA Burlington
- Assignee: EMD Millipore Corporation
- Current Assignee: EMD Millipore Corporation
- Current Assignee Address: US MA Burlington
- Agency: EMD Millipore Corporation
- International Application: PCT/US2014/021802 WO 20140307
- International Announcement: WO2014/159064 WO 20141002
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K16/06 ; B01D15/16 ; B01D15/38 ; C07K1/36

Abstract:
The present invention provides methods for increasing purity of an Fc-containing protein by removing protein aggregates during the Protein A chromatography step used during the purification of the Fc-containing protein.
Public/Granted literature
- US20160122385A1 METHODS OF INCREASING PROTEIN PURITY USING PROTEIN A BASED CHROMATOGRAPHY Public/Granted day:2016-05-05
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