Non-volatile (NV) memory (NVM) matrix circuits employing NVM circuits for performing matrix computations are disclosed. In exemplary aspects disclosed herein, an NVM matrix circuit is provided that has a plurality of NVM storage string circuits each comprising a plurality of NVM bit cell circuits each configured to store a memory state. Each NVM bit cell circuit has a stored memory state represented by a resistance, and includes a transistor whose gate node is coupled to a word line among a plurality of word lines configured to receive an input vector of 1×m size for example. Activation of the gate of a given NVM bit cell circuit controls whether its resistance is contributed to a respective source line. This causes a summation current to be generated on each source line based on the weighted summed contribution of each NVM bit cell circuit's resistance to its respective source line.