- 专利标题: Grafting of cyclodextrin by amide bonds to an ether cross-linked hyaluronic acid and uses thereof
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申请号: US15537228申请日: 2015-12-17
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公开(公告)号: US10533061B2公开(公告)日: 2020-01-14
- 发明人: Jean-Guy Boiteau , Elin Säwén
- 申请人: GALDERMA S.A.
- 申请人地址: CH Cham
- 专利权人: Galderma S.A.
- 当前专利权人: Galderma S.A.
- 当前专利权人地址: CH Cham
- 代理机构: Foley & Lardner LLP
- 代理商 Sunit Talapatra
- 优先权: EP14198793 20141218
- 国际申请: PCT/EP2015/080346 WO 20151217
- 国际公布: WO2016/097211 WO 20160623
- 主分类号: C08B37/16
- IPC分类号: C08B37/16 ; C08B37/08 ; A61K47/69 ; A61K8/04 ; A61K8/73 ; A61K9/06 ; A61Q19/00
摘要:
A hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more cyclodextrin molecules are grafted onto the cross-linked hyaluronic acid by amide bonds, preferably using a triazine-based coupling reagent. A process of preparing a hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules.
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