Invention Grant
- Patent Title: Cycloalkylamines as monoamine reuptake inhibitors
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Application No.: US15836261Application Date: 2017-12-08
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Publication No.: US10562878B2Publication Date: 2020-02-18
- Inventor: Liming Shao , Fengjiang Wang , Scott Christopher Malcolm , Michael Charles Hewitt , Larry R. Bush , Jianguo Ma , Mark A. Varney , Una Campbell , Sharon Rae Engel , Larry Wendell Hardy , Patrick Koch , John E. Campell
- Applicant: Sunovion Pharmaceuticals Inc.
- Applicant Address: US MA Marlborough
- Assignee: SUNOVION PHARAMCEUTICALS INC.
- Current Assignee: SUNOVION PHARAMCEUTICALS INC.
- Current Assignee Address: US MA Marlborough
- Main IPC: C07D333/20
- IPC: C07D333/20 ; C07C211/17 ; C07C211/40 ; C07C215/42 ; C07C215/44 ; C07C217/52 ; C07C217/74 ; C07C323/32 ; C07D207/06 ; C07D207/08 ; C07D211/14 ; C07D265/14 ; C07D277/28 ; C07D295/06 ; C07D307/52 ; C07D317/58 ; C07D317/72 ; C07D319/06 ; C07D491/056 ; C07C211/29 ; C07D211/16
Abstract:
The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.
Public/Granted literature
- US20180230120A1 CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS Public/Granted day:2018-08-16
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