Invention Grant
- Patent Title: Antibodies specific for hyperphosphorylated tau and methods of use thereof
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Application No.: US16188489Application Date: 2018-11-13
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Publication No.: US10562962B2Publication Date: 2020-02-18
- Inventor: Jan Torleif Pedersen , Lars Østergaard Pedersen , Justus Claus Daechsel , Ayodeji Abdur-rasheed Asuni , Nina Helen Rosenqvist , Christiane Volbracht , Lone Helboe , Anders Brandt Elvang , Florence Sotty , Søren Christensen , Jeffrey B. Stavenhagen
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: GB1512211.2 20150713; GB1518375.9 20151016
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K39/395 ; G01N33/68 ; A61K49/00 ; A61K39/00
Abstract:
The present invention relates to a novel class of monoclonal antibody that specifically binds the phosphorylated serine 396 residue on pathological hyperphosphorylated (PHF) tau (pS396), as well as to methods of using these molecules and their tau binding fragments in the treatment of Alzheimer's disease and tauopathies.
Public/Granted literature
- US20190177401A1 ANTIBODIES SPECIFIC FOR HYPERPHOSPHORYLATED TAU AND METHODS OF USE THEREOF Public/Granted day:2019-06-13
Information query
