- 专利标题: Treatment of diseases related to alpha subunits of sodium channels, voltage-gated (SCNxA) with small molecules
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申请号: US14343890申请日: 2012-08-28
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公开(公告)号: US10583128B2公开(公告)日: 2020-03-10
- 发明人: Joseph Collard , Olga Khorkova Sherman , Jane H. Hsiao
- 申请人: Joseph Collard , Olga Khorkova Sherman , Jane H. Hsiao
- 申请人地址: US FL Miami
- 专利权人: CuRNA, Inc.
- 当前专利权人: CuRNA, Inc.
- 当前专利权人地址: US FL Miami
- 代理机构: CuRNA, Inc.
- 代理商 Monte R. Browder
- 国际申请: PCT/US2012/052685 WO 20120828
- 国际公布: WO2013/036403 WO 20130314
- 主分类号: A61K31/7048
- IPC分类号: A61K31/7048 ; A61K31/4545 ; A61K31/496 ; A61K31/58 ; A61K31/495 ; A61K31/5513 ; A61K31/436 ; A61K31/5375 ; A61K31/519 ; A61K31/4985 ; A61K31/4409 ; A61K31/4439 ; A61K31/4422 ; A61K31/365 ; A61K31/64 ; A61K31/41 ; A61K31/135 ; A61K31/165 ; A61K31/4245
摘要:
Small compounds that modulate the expression of and/or function of sodium channel, voltage-gated, alpha subunit (SCNxA) are presented. Pharmaceutical compositions containing such small molecules and their use in treating diseases and disorders associated with the expression of SCNxA are also presented.
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