Invention Grant
- Patent Title: SHMT inhibitors
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Application No.: US16103375Application Date: 2018-08-14
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Publication No.: US10584132B2Publication Date: 2020-03-10
- Inventor: Joshua D. Rabinowitz , Hahn Kim , Gregory S. Ducker , Jonathan M. Ghergurovich
- Applicant: The Trustees of Princeton University
- Applicant Address: US NJ Princeton
- Assignee: The Trustees of Princeton University
- Current Assignee: The Trustees of Princeton University
- Current Assignee Address: US NJ Princeton
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K31/4162
- IPC: A61K31/4162 ; C07D491/052 ; A61K31/19 ; A61K31/496 ; A61K31/198 ; A61K45/06
Abstract:
The disclosure provides compounds of Formulae (I)-(IX). The disclosed compounds are capable of inhibiting a mammalian SHMT. Compounds of the disclosure have numerous uses, such as for treatment of cancer or autoimmue disorders.
Public/Granted literature
- US20180354964A1 SHMT Inhibitors Public/Granted day:2018-12-13
Information query
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