Invention Grant
- Patent Title: Biphenyl amides with modified ether groups as HSP90 inhibitors and HSP70 inducers
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Application No.: US15321289Application Date: 2015-06-24
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Publication No.: US10590065B2Publication Date: 2020-03-17
- Inventor: Brian S. J. Blagg , Rick T. Dobrowsky , Mercy Anyika
- Applicant: THE UNIVERSITY OF KANSAS
- Applicant Address: US KS Lawrence
- Assignee: UNIVERSITY OF KANSAS
- Current Assignee: UNIVERSITY OF KANSAS
- Current Assignee Address: US KS Lawrence
- Agency: Parker Highlander PLLC
- International Application: PCT/US2015/037478 WO 20150624
- International Announcement: WO2015/200514 WO 20151230
- Main IPC: C07C233/18
- IPC: C07C233/18 ; C07D309/10 ; C07H15/203 ; C07D307/20 ; C07D311/08 ; C07D311/16
Abstract:
Provided herein are compounds of the formulas: (I) wherein: n, X2, R3, R3′, R4, R4′, R5, R5′, R6, and R6′ are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer.
Public/Granted literature
- US20180057446A1 BIPHENYL AMIDES WITH MODIFIED ETHER GROUPS AS HSP90 INHIBITORS AND HSP70 INDUCERS Public/Granted day:2018-03-01
Information query
