Invention Grant
- Patent Title: Neuronal modulation
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Application No.: US15037412Application Date: 2014-11-26
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Publication No.: US10603315B2Publication Date: 2020-03-31
- Inventor: Asya Rolls , Tamar Ben Shannan , Hilla Azulay-Debbie , Fahed Hakim , Maya Schiller , Shai Shen-Orr , Elina Starosvetsky
- Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED , HEALTH CORPORATION—RAMBAM , THE RAPPAPORT INSTITUTE
- Agency: Roach Brown McCarthy & Gruber, P.C.
- Agent Kevin D. McCarthy
- International Application: PCT/IL2014/051026 WO 20141126
- International Announcement: WO2015/079439 WO 20150604
- Main IPC: A61N2/00
- IPC: A61N2/00 ; A61N2/02 ; A61K31/48 ; A61K31/428 ; A61K31/473 ; A61K31/506 ; A61K31/404 ; A61K31/4045
Abstract:
A method for modulating an immune response by activating or inhibiting dopaminergic neurons in the Ventral Tegmental Area (VTA) is provided. Modulation is achieved by modulating the activity, the abundance or both of: a natural killer cell, a CD8 T-cell, a CD4 T-cell, a B-cell, a dendritic cell, a macrophage, a granulocyte, or their combination.
Public/Granted literature
- US20160287577A1 NEURONAL MODULATION Public/Granted day:2016-10-06
Information query
