Invention Grant
- Patent Title: Separation matrix
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Application No.: US15282367Application Date: 2016-09-30
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Publication No.: US10654887B2Publication Date: 2020-05-19
- Inventor: Gustav Jose Rodrigo , Tomas Bjorkman , Mats Ander , Jesper Ulf Hansson
- Applicant: GE Healthcare BioProcess R&D AB
- Applicant Address: SE Uppsala
- Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee: GE Healthcare Bio-Process R&D AB
- Current Assignee Address: SE Uppsala
- Agency: Eversheds Sutherland (US) LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@64fc0311
- Main IPC: C07K1/22
- IPC: C07K1/22 ; B01J20/26 ; C07K16/00 ; C07K14/31 ; B01J20/32 ; B01J20/285 ; B01J20/286 ; C07K16/12 ; C07K17/10
Abstract:
The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein: a) the ligands comprise multimers of alkali-stabilized Protein A domains, and b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50,v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.
Public/Granted literature
- US20170327534A1 SEPARATION MATRIX Public/Granted day:2017-11-16
Information query
