Invention Grant
- Patent Title: Microorganisms for producing 4C-5C compounds with unsaturation and methods related thereto
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Application No.: US15323360Application Date: 2015-07-02
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Publication No.: US10669561B2Publication Date: 2020-06-02
- Inventor: Stephanie J. Culler , Mark J. Burk , Robin E. Osterhout , Priti Pharkya
- Applicant: Genomatica, Inc.
- Applicant Address: US CA San Diego
- Assignee: GENOMATICA, INC.
- Current Assignee: GENOMATICA, INC.
- Current Assignee Address: US CA San Diego
- Agency: Kagan Binder, PLLC
- International Application: PCT/US2015/039037 WO 20150702
- International Announcement: WO2016/004334 WO 20160107
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N1/20 ; C12N9/00 ; C12N9/02 ; C12N9/88 ; C12N9/90 ; C07H21/04 ; C12P7/04 ; C12N15/52 ; C12P5/02 ; C12P7/40 ; C12N9/04
Abstract:
The invention provides a non-naturally occurring microbial organism having a butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol, pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in a pathway. The invention additionally provides a method for producing butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol. The method can include culturing a butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol-producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding a pathway enzyme in a sufficient amount, and under conditions and for a sufficient period of time to produce butadiene, crotyl alcohol, 2,4-pentadienoate, 3-buten-2-ol, or 3-buten-1-ol.
Public/Granted literature
- US20170166931A1 MICROORGANISMS FOR PRODUCING 4C-5C COMPOUNDS WITH UNSATURATION AND METHODS RELATED THERETO Public/Granted day:2017-06-15
Information query
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